I did notice some safety concerns regarding a few of the medications. For example, Cholestyramine interacts with Acetaminophen and Metoprolol if they are taken at the same time and while taking Apixaban consuming grapefruit juice should be avoided. There were more safety concerns noted but a lot of them were related to timing and food/drug interactions that should be avoided. This would be more related to my patients understanding of these medications. My patient has a clear understanding why she is on each medication. This is important because it increases their ability to comply with the medication regimen they are on. My patient takes Apixaban, Cholestyramine, and Aspirin for treatment of atrial fibrillation. She does understand why she is taking these various medications to treat her condition. There were no serious medication interactions that she was not aware of.